The purpose of treatment of hyperuricemia is to reduce blood uric acid, prevent urate deposition, quickly stop the onset of acute arthritis, and prevent the formation of uric acid stones and renal function damage. Blood uric acid control target: control within 420μmol/L in asymptomatic patients and below 360μmol/L in patients with comorbidities. The treatment of hyperuricemia requires rational drug use, both prevention and treatment, diet control, weight control and appropriate increase of physical activity.
Dietary advice
01 Diet should be dominated by low purine foods
The daily purine content should be controlled under 200mg, and the intake of animal foods with high purines should be avoided, such as animal offal, seafood, thick broth and gravy, etc. The intake of beef, mutton and pork should be limited, and poultry and freshwater fish should be preferred. Eat more vegetables, fruits and milk.
02 Drink more water
It is recommended to maintain a daily water intake of more than 2000ml, can be drinking water, tea or unsweetened coffee, avoid sugary juices, sugary drinks, including freshly squeezed orange juice, apple juice, grape juice, pear juice, etc.
03 Limit alcohol consumption
It is beer and liquor, wine; Total alcohol consumption < 28g/d for males and < 14g/d for females.
04 Milk eggs every day
Recommended daily low-fat milk 250ml-300ml; Egg yolks are not more than 1 per day, and egg whites can be 1-2 per day.
05 Diet less salt, less oil, sugar control
Exercise suggestion
01 Do not strenuous activities
Physical exercise should be stopped during gout attacks. Patients with incomplete remission of gout should not participate in strenuous exercise or prolonged physical work, such as playing ball, jumping, running, climbing, long-distance walking, traveling, etc. These intense and long-term exercises can increase sweating, reduce blood volume and renal blood flow, reduce excretion of uric acid and creatine, aggravate hyperuricemia, and induce gout attacks.
02 Adhere to reasonable exercise methods
People with gout should not exercise vigorously, but they can choose some simple exercises. Such as walking, walking at a constant speed, Taijiquan, aerobics, Qigong, cycling and swimming, among which walking, cycling and swimming are the most suitable.
Drug suggestion
01 Drugs that increase uric acid excretion
Such as benzenbromarone tablets, Bingsulfa tablets and other drugs, by increasing the excretion of uric acid to reduce the level of uric acid in the body, in the process of use to drink more water, maintain sufficient urine volume, to prevent the formation of uric acid crystals.
02 Inhibit uric acid synthesis drugs
Such as allopurinol tablets, febuxosita tablets, can inhibit uric acid production, reduce the concentration of uric acid in the blood. Patients with positive HLA-B*5801 are at a much higher risk of exfoliative dermatitis after allopurinol, and genetic testing is recommended before taking allopurinol to reduce the risk of serious skin adverse reactions.
03 Alkalized urine
It is recommended that patients with hyperuricemia and gout, especially when taking uricotropin excretion drugs, should monitor the pH of morning urine regularly; When the pH value is < 6.0, it is recommended to take citric acid preparations and sodium bicarbonate to alkalize urine, in order to reduce the risk of uric acid kidney stones and facilitate the dissolution of uric acid kidney stones.
04 Non-steroidal anti-inflammatory drugs
If you have symptoms such as redness, swelling and pain in the joints, you should take non-steroidal anti-inflammatory drugs for antipyretic and analgesic treatment, such as ibuprofen sustained-release capsules or diclofenac sodium enteric-coated tablets.
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Post time: Sep-23-2024